Let me provide a context so that you may understand my amazement with the chemical explorations of Alexander Shulgin. Did you know that the two principal neurotransmitters in the human body are dopamine and serotonin? Did you know that they belong to the phenethylamine and tryptamine chemical families, respectively? I find this simple observation to be of fundamental importance in understanding the human mind/body relationship. And now consider that Ann and Alex Shulgins’ books: PiKHAL (Phenethylamines I have known and loved) and TiKHAL (Tryptamines I have known and loved) explore both these chemical families and their effects on the human mind and body. Quick summary of well-known psychedelic chemicals:

LSD is complex and has both chemical structures, but most people emphasize that the effects of LSD are related primarily to its tryptamine backbone and interaction with human serotonin receptors.

Ann and Alexander Shulgin’s books are a groundbreaking revelation for their accounts of psychedelic exploration, therapy, and spiritual development. They are a mix of essays and stories. You will not regret reading the books and learning about the chemicals referenced in the second half of the books.

An interesting note: In PiKHAL, the fictional character Adam Fisher is based on Leo Zeff, a talented psychotherapist who worked with MDMA; you can read all about his therapy work in The Secret Chief Revealed by Myron J. Stolaroff.